What I Tell Anyone Who Struggles With Inflammation + How To Get Back To Optimal Health - Dr. Will Cole
Chicken and Mushroom Stroganoff - Amy Myers MD
- 1 (4.5lb) whole chicken (or rotiserrie chicken)
- 2 tsp olive oil
- 1/3 cup shallot chopped
- 1/2 tsp kosher salt
- 1 8oz package cremini mushroom
- 2 tsp arrowroot starch
- 1 cup bone broth
- 1/3 cup unsweetened coconut yogurt plain flavor
- 1 tbsp tarragon chopped
- 1/4 tsp ground black pepper
- Optional: zucchini, butternut squash, or sweet potato noodles
Instructions
- If cooking chicken from scratch, prepare whole chicken.
- Once chicken is cooked through, remove meat from 1 breast and 1 thigh and shred.
- Heat oil in a large skillet over medium heat. Add shallots and satuée for 1 minute or until translucent. Add mushrooms and cook until soft, about 4 minutes. Add arrowroot starch to pan and stir constantly for 1 minute.
- Add in 1 cup of bone broth and let simmer for 2-3 minutes or until sauce has thickened. Add in chicken, coconut yogurt, and seasonings. Serve as is or with veggie noodles.
Medications Should be Labeled 'Gluten Free,' Says FDA | American Council on Science and Health
For people living with celiac disease, everything that goes into the body has to be assessed for gluten. Even tiny amounts (trace amounts) of gluten can cause illness in some people with celiac disease. In order to do that, people need to know what they are putting into their bodies.
One very effective way that this has been handled for the celiac community is the mandatory labeling of gluten free foods set by the Food and Drug Administration (FDA). Those efforts were mostly focused on food. But, because the concern extends to everything that is ingested - including medications - so too should the labeling says FDA.
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Surprising Number of Conditions Linked to Celiac Disease
The rate of celiac disease is almost 20 times higher in people with autism than in those without, reported lead investigator Daniel Karb, MD, a second-year resident at University Hospitals Case Medical Center in Cleveland.
"If you have a patient who is autistic and they have all these unusual symptoms, you might want to screen them for celiac disease," he said here at the World Congress of Gastroenterology 2017.
It is known that there are unusual symptoms of celiac disease, which include anything outside the classic symptoms of malabsorption, steatorrhea, malnutrition, abdominal pain, and cramping after eating, "but this is putting numbers to it," said Dr Karb.
He and his colleagues searched the Explorys database, which aggregates electronic health record data from 26 major integrated healthcare systems in the United States. Of 35,854,260 people in the database, 83,090 were diagnosed with celiac disease from 2012 to 2017.
Overall, the age-adjusted prevalence of celiac disease was 0.22%, which is lower than the 1% to 2% range previously estimated.
If you have a patient who is autistic and they have all these unusual symptoms, you might want to screen them for celiac disease.
"We don't think there are fewer people with celiac disease, just that it may be underdiagnosed," Dr Karb told Medscape Medical News. "We found that the prevalence was a little bit less at these screening sites, which is what you might expect when you screen asymptomatic people."
"It tells us there is a large undiagnosed burden of celiac disease," he explained. "And a lot of it is probably because of these atypical presentations."
The investigators found a significant association between celiac disease and 13 other autoimmune disorders, such as type 1 diabetes, Crohn's disease, and ulcerative colitis. "Every autoimmune disease we looked at is associated with celiac disease, other than primary biliary cholangitis." Dr Karb reported.
"I was surprised at the findings," he said. "I thought there would be associations. I didn't realize how striking they would be."
Table 1. Prevalence of Diagnoses in People With and Without Celiac Disease (P < .0001 for All)
| Diagnosis | With Celiac Disease, % | Without Celiac Disease, % | Odds Ratio |
|---|---|---|---|
| Migraine | 18.6 | 4.1 | 5.5 |
| Anxiety disorder | 25.9 | 8.7 | 4.0 |
| Arthritis | 28.9 | 8.4 | 4.9 |
| Dermatitis herpetiformis | 1.3 | 0.0 | 4563.5 |
| Liver disease | 23.2 | 4.2 | 7.1 |
| Gastroesophageal reflux disease | 36.8 | 13.0 | 4.5 |
| Eosinophilic esophagitis | 0.6 | 0.1 | 8.8 |
| Atrophic gastritis | 3.9 | 0.1 | 8.0 |
| Glossitis | 0.4 | 0.1 | 4.4 |
| Pancreatitis | 15.8 | 0.7 | 25.0 |
| Disorder of the pancreas | 17.2 | 1.1 | 19.0 |
| Cerebellar ataxia | 0.1 | 0.0 | 4.1 |
| Autism | 4.0 | 0.2 | 19.9 |
| Colitis | 25.9 | 4.2 | 8.4 |
| Turner syndrome | 0.1 | 0 | 17.8 |
| Down syndrome | 0.6 | 0.1 | 8.1 |
| Common variable immunodeficiency | 0.2 | 0.0 | 10.2 |
Celiac disease serology testing can be warranted "if you've gone through everything and the person doesn't get better," Dr Karb pointed out. However, a positive celiac disease serology test generally leads to more invasive colonoscopy with histology testing, he cautioned.
"You don't want to overtest because you don't want to be giving invasive biopsies to people who may be asymptomatic, even if they do have celiac disease. It will take some careful thought," he explained.
For this reason, the investigators are not recommending new screening guidelines on the basis of their findings. But, Dr Karb suggested, "we could take our strongest associations and include them in existing guidelines."
"This study indicates that celiac disease has a relatively low incidence in the target population studied, such that national screening is probably not cost-effective," said Stephen Middleton, MD, from Cambridge University Hospitals in the United Kingdom.
"In this context, knowing when to have a high level of suspicion is important," he told Medscape Medical News.
"The association of celiac with other disorders, as described in the abstract, is very important," he added. "This is especially important for conditions such as pancreatitis and eosinophilic esophagitis, which can be very difficult to treat."
Dr Karb and Dr Middleton have disclosed no relevant financial relationships.
World Congress of Gastroenterology 2017: Abstract P2447. Presented October 17, 2017.
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